ABSTRACT
Objective: The study aims to evaluate the emotional, behavioural, and social effects of single or multiple anterior tooth loss. It also compares the effectiveness of the removable and fixed prosthesis to address the impact of anterior tooth loss. Material and Methods: The study was carried out on 70 subjects who presented to the Department of Prosthetic Dental Sciences. A questionnaire was distributed and the data were statistically analyzed using SPSS version 18.0 and values less than 0.05 % were considered statistically significant. Results: The participant's difficulty to accept loss of their anterior tooth, embarrassment and confidence were changed significantly after wearing the prosthesis (P< 0.05). Moreover, fixed partial denture had more effect than removal partial denture. It was claimed by 62.9% of the participants that they were not prepared for the effect of tooth loss and 47.1% of them thought that a prior explanation from the dentist would have helped them overcome their fear of losing their teeth. Conclusion: The maximum impact of anterior tooth loss was felt on confidence followed by embarrassment. The participants felt more comfortable after wearing their prosthesis. Fixed partial denture had more effect than removable partial denture.(AU)
Objetivo: O estudo visa avaliar os efeitos emocionais, comportamentais e sociais da perda dentária anterior unitária ou múltipla. Ele também compara a eficácia da protese removível e da fixa para lidar com o impacto da perda dentária anterior. Material e Métodos: O estudo foi realizado em 70 indivíduos que se apresentaram ao Department of Prosthetic Dental Sciences. Foi distribuído um questionário e os dados analisados estatisticamente no SPSS versão 18.0 e valores inferiores a 0,05% foram considerados estatisticamente significativos. Resultados: A dificuldade do participante em aceitar a perda de seu dente anterior, constrangimento e confiança mudaram significativamente após usar a prótese (P <0,05). Além disso, a prótese parcial fixa teve mais efeito do que a prótese parcial removível. Foi alegado por 62,9% dos participantes que não estavam preparados para o efeito da perda dentária e 47,1% deles achavam que uma explicação prévia do cirurgião-dentista os teria ajudado a superar o medo de perder os dentes. Conclusão: O impacto máximo da perda dentária anterior foi sentido na confiança, seguido de constrangimento. Os participantes se sentiram mais confortáveis após o uso de suas próteses. A prótese parcial fixa teve mais efeito do que a prótese parcial removível (AU)
Subject(s)
Humans , Tooth Loss , Dental Prosthesis , Emotional AdjustmentABSTRACT
The purpose of this study was to assess and compare the dimensional accuracy of the stone casts made of three extended pour alginate impressions materials (Cavex Colorchange, Kromopan, and Neocolloid) following storage under different storage conditions and pouring at different time intervals. Materials and Methods: A maxillary Frasaco (dentulous) model was selected as a standard model. Index holes of 1 mm depth and 1 mm diameter were made on the palatal cusp tips of right and left first premolars, mesiopalatal cusp tips of right and left third molars and in the midline of the palate, perpendicular to a line joining the index holes made on cusp tips of the first premolars as reference points for measurement. A single uniformly spaced custom tray was fabricated with heat-cure acrylic resin and used to make impressions for the entire study. A total of 210 impressions of the master model were made, seventy impressions were made from each of the alginate material brands and were subjected to three storage conditions (open air, uncontrolled humidity, and 100% controlled humidity) for three different storage time intervals (0, 1, 6 h). Since no storage was done in the immediate-pour group, it contained 10 specimens from each brand. Following the designated storage time interval, all impressions were poured in type IV gypsum. Measurements of stone casts were done in three dimensions, anteroposterior, lateral using Measuroscope and vertical by Dial Gauge. Data were organized in tables and statistical analyses were performed. Three-way ANOVAs were used to check if the material brands, storage time intervals, and conditions affect the measurements. Tukey HSD post hoc tests were used for the multiple comparisons if ANOVA is significant. One sample t-test was used to compare between the casts made of alginate brands and the master model. Significance level was set to α < 0.05 for all tests. Results: Results showed that the material brands, storage time intervals, and conditions do affect the measurements in all three dimensions (all P < 0.05). In addition, all two-way and three-way interactions were significant for all measurements except the interaction of storage time intervals and conditions for B–C (lateral) measurements, and interaction of material brands and storage time intervals for C–D (anteroposteriorly) measurements. When stone casts were compared to the master model, immediate pour, and storage for 1 h in 100% controlled humidity resulted in statistically insignificant changes among all three alginate impression brands. In addition, the specimens made of Cavex Colorchange and Kromopan following storage in uncontrolled humidity condition for 1 h showed statistical insignificance when compared to the master model. Conclusion: Within the limitations of this study, it can be extrapolated that, although this class of alginate impression materials was manufactured for extended pour purposes, clinicians should avoid storage of the studied brands for 6 h. Whenever 1 h to pour is necessary, 100% controlled humidity is the ideal and standardized environment for all three alginate brands. Perhaps, Cavex Colorchange, and Kromopan can be safely stored in uncontrolled humidity condition while maintaining their optimal dimensional accuracy.
ABSTRACT
Background: the prevalence of esophageal varices [OV] in newly diagnosed cirrhotic patients is approximately 60-80% and the 1-year rate of first variceal bleeding is approximately 5% for small esophageal varices and 15% for large esophageal varices. Non invasiveness has become a major goal in hepatology in the latter years, several serum markers and imaging methods have been tried for the non invasive assessment of portal hypertension or presence of esophageal varices
Aim of the work: this study aimed to compare ALBI, MELD and Child-pugh scores in prediction of esophageal varices and for discrimination between risky and non risky esophageal varices
Methods: in this Prospective study evaluation of of ALBI, MELD And Child-Pugh Scores As non-Invasive Predictors of Esophageal Varices was done in 80 patients with liver cirrhosis. They were divided into 2 groups, Group I: included 60 patients with liver cirrhosis and esophageal varices diagnosed by upper GIT endoscopy and will be divided into 3 subgroups 20 patients each as described below: Small, Moderate and Large esophageal varices. Group II: included 20 patients with liver cirrhosis with no esophageal varices as the control groupg
Results: the current study showed that ALBI score could be used as a non invasive predictor of esophageal varices with a cut-off value > - 2.2, with 96.7% sensitivity, 100% specificity, Child score could be used with a cut-off value > 5.5, with 93.3% sensitivity, 100% specificity, and MELD score could be used with a cut-off value > 8.5, with 90% sensitivity, 95% specificity
Conclusion: ALBI score is more accurate than Child and MELD scores as non invasive predictor of esophageal varices and its grading
ABSTRACT
This study compared PCR and Western blot techniques in diagnosis of schistosomiasis mansoni. Forty Swiss albino mice were used, thirty two mice were infected with cercariae of S. mansoni and eight mice were kept uninfected which were used as a control. Blood was obtained from four infected mice weekly beginning from the 1[st] week to the 8[th] week post infection. The study found that PCR was positive from the first week post infection, while Western blot technique was positive from the second week post infection. Thus, PCR diagnosed schistosomiasis mansoni earlier than Western blot technique, but both were able to diagnose
Subject(s)
Animals, Laboratory , Polymerase Chain Reaction , Blotting, Western , Mice , Antigens, Helminth , DNA, HelminthABSTRACT
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide and the prognosis still remains dismal, so the present work was planned to assess the prognostic value of Ki67 in mice model of HCC induced by diethylnitrosamine (DEN), in addition to its correlation to the histopathological changes. Forty male Swiss albino mice were randomly divided into two groups; group I: 10 mice were served as controls and group II: 30 mice were injected i.p with DEN at a dose of 75 mg/kg b.w once /week for three weeks then 100 mg/kg b.w for another 3 weeks. Mice were sacrificed after 6, 12 and 18 weeks from the beginning of the experiment. Liver specimens were processed for histopathological examination and immunohistochemical expression of Ki67. Results of histopathological study revealed spotty necrosis with enlarged nuclei and cholestasis 6 weeks after DEN injection. Proliferation of bile ducts, perivenous focal apoptosis and increased number of cells acquiring large nuclei were prominent after 12 weeks. Deleterious effect of DEN was obvious after 18 weeks; where HCC features were seen as sheets of malignant hepatocytes, multinodular areas of coagulative necrosis and nodule of ghosts' necrotic hepatocytes. Collagen deposition was time dependent and showed maximum level around and within nodules in HCC after 18 weeks. Immunohistochemical expression of Ki67 showed increased positivity after 6 and 12 weeks and the highest increase in the number of Ki67 positive cells after 18 weeks of DEN injection. Conclusion: Based on the previous data, it could be concluded that ki67 can be used as a biological marker for prognosis of HCC.
ABSTRACT
Background: Helicobacter pyloriis is a Gram negative, bacterium that colonizes human gastric mucosa and is one of the most common bacterial pathogens worldwide with prevalence of up to 90 % in developing Countries. It is the primary cause of peptic ulcer disease and an etiologic agent in the development of gastric cancer. H. pylori infection is curable with regimens of multiple antimicrobial agents. However, antibiotic resistance is a leading cause of treatment failure. The aim of this study is to assess the prevalence of H.pylori in gastric biopsies taken from Egyptian patients by using invasive methods and study the role of antimicrobial agents in elimination of this bacterium
Methodology: From 50 patients, 3 antral gastric biopsies were taken from the greater curvature about 2 cm, from pylorus. The first biopsy was for direct Gram's stain and culture [using Blood agar] to apply Traditional Biochemical tests and antimicrobial susceptibility test to different antibiotics, The second biopsy was used for rapid urease test [using modified Christensen's urea broth] and the third biopsy was kept in deep, freezer at -70 C in brain heart infusion broth for PCR assay using Ure c gene
Results: Among 50 patients, 22[44%] were positive by culture, 17[34%] were positive by direct Gram's stain with 77.3% sensitivity, 100% specificity and 90% accuracy, while 19[38%] were positive by rapid urease test with 63.6% sensitivity, 82.1% specificity and 74% accuracy, and 25[50%] were positive by PCR with 95.5% sensitivity, 89.3% specificity and 92% accuracy .By antimicrobial Susceptibility testing using disc diffusion method, it was shown that the highest susceptibility of the isolated H.pylori strains was to amoxicillin [90.9%] followed by tetracycline [81.8%], Gentamicin [54.5%] Erythromycin [18.2%] and Ciprofloxacin [9.1 %]. However no one [zero %] was highly sensitive to Metronidazole
Conclusion: Some of antibiotics widely used in Egypt are no longer suitable for treatment of Helicobacter pylori and new antibiotics regimen are needed to eradicate this organism
ABSTRACT
Irritable bowel syndrome [IBS] can be diagnosed at any age but a new diagnosis of IBS should be made in patients older than 60 years of age because other diseases [colon cancer, diverttculitis, inflammatory bowel may have similar presenting symptoms. Research studies consistently show that women are two to three times more likely than men to be diagnosed with IBS, Over 40 years ago, it was recognized that a percentage of patients with irritable colon developed typical IBS symptoms after an acute infective enteritis [eg, postdysentery IBS]. The aim of the present work to study the relationship between helicobacter pylori and irritable bowel syndrome. The present study was conducted on 30 subjects, They were stratified into 2 groups: group I [IBS groups], they were twenty patients with symptoms suggestive of irritable bowel syndrome according to Rome criteria II, they were 6 males [30%] and 14 females [70%] and their ages were ranging from 18 to 50 years with a mean value of [36.5 +/- 13.2 years] and this group underwent upper endoscopy and colonoscopy and random biopsies were taken from gastric and colonic mucosa for histological examination. Group II [control group] included ten healthy volunteers with no symptoms suggestive of irritable bowel syndrome, they were [5] males and [5] females matched by age They were chosen from referrals to the endoscopy unit of Menoufiya University Hospital. An informed consent was obtained from all included subjects. There was statistically significant difference in the results of histopathological examination of biopsies taken from the colon. There is increase in inflammatory cell infiltration of mucosa of the colon of IBS patient than control groups [lymphocyte infiltration, plasma cell and eosinophit. Helicobacter pylori [HP] did not colonize the colon mucosa. There was no a statistically significant difference in the results of hisiopathological examination of biopsies taken from the gastric antrum of IBS patient and control group [inflammatory cell infiltration]. There was no statistically significant difference of presence of HP in the gastric mucosa of IBS patients and healthy control. No direct correlation between HP infection and IBS but there was intense inflammatory response in the presence of HP
Subject(s)
Humans , Male , Female , Colonic Diseases, Functional/diagnosis , Helicobacter Infections/diagnosis , Prevalence , Helicobacter pylori , Endoscopy, Gastrointestinal , Colonoscopy , Biopsy , Histology , Signs and Symptoms, Digestive , SyndromeABSTRACT
The risks to the mother and newborn associated with the use of vacuum extractor [V.E.] in comparison with those associated with the use of low delivery forceps [L.D.F.] were studied prospectively. Sixty-nine women were enrolled into the study, all with single, term [37 weeks or more] babies, with cephalic presentation, required assisted vaginal deliveries. They were randomized to either vacuum group [38] or forceps [31]. Third degree perineal tears, vaginal and cervical lacerations, requirement of blood transfusion were observed less frequently in the group delivered by V.E., the differences were not statistically significant. One baby in the vacuum group developed cephalohaematoma. The vacuum group had a less stay in hospital [more than 48 hours] than the forceps group and the difference is statistically significant. There were no significant differences in the mean birth weight, Apgar scores and the numbers of babies admitted to the intensive care unit. One baby delivered by forceps died shortly after birth. There was no maternal death in either group